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Chiral biphenyl pharmaceutical intermediates

Optically active biphenyl derivatives for the synthesis of active pharmaceutical ingredients.

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Summary table for this section

Substance Chemical formula CAS number Applications
(R,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid C23H27NO4 1012341-48-8 Boc-protected chiral intermediate for drug substances.
(R)-3-([1,1'-Biphenyl]-4-yl)-2-aminopropan-1-ol C15H17NO 1426129-52-3 Chiral intermediate for pharmaceutical substances.
(S)-1-([1,1'-Biphenyl]-4-yl)-3-chloropropan-2-ol C15H15ClO 1573000-28-8 Chiral building block for active pharmaceutical ingredients.
tert-Butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate C20H25NO3 1426129-50-1 Boc-protected chiral intermediate for pharmaceutical synthesis.

Data is taken from the manufacturer's 2026 catalog. Specifications are confirmed when ordering and may be changed by the manufacturer.